1、分子转子型荧光染料的构建

2、核酸和蛋白质等生物大分子荧光标记技术的开发

3、活细胞及活体动物的特异性荧光成像

教育科研背景

2026年5月至今                    伟德bv1946官网       特聘副研究员

2021年7月至2026年4月       上海交通大学       博士后

2016年9月至2021年6月       伟德bv1946官网        硕博

2012年9月至2016年6月          广西大学               本科

代表性论文

(1) Li Jiang;  Xin Xie; Ni Su; Dasheng Zhang; Xianjun Chen*; Xiaochen Xu; Bibi Zhang; Kaiyi Huang; Jingwei Yu; Mengyue Fang; Bingkun Bao; Fangting Zuo; Lipeng Yang; Rui Zhang; Huiwen Li; Xinyi Huang; Zhengda Chen; Qingmei Zeng; Renmei Liu; Qiuning Lin; Yuzheng Zhao; Aiming Ren*; Linyong Zhu*; Yi Yang*; Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells, Nature Methods, 2023, 20: 1563-1572.

(2) Zhengda Chen, Li Jiang (Co-first author), Xiaoyu Liu, Yajie Shi, Yang Liu, Ling Jiang, Jiaxin Li, Xinyi Huang, Siyu Zhou, Bingkun Bao, Bibi Zhang, Qiuning Lin, Qi Bian, Yuxin Yin, Fangting Zuo, Ni Su, Yun Tang, Yuzheng Zhao, Yi Yang *, Xianjun Chen *, Linyong Zhu *,NirFAP680: A Highly Bright and Stable Large Stokes Shift Near-Infrared Fluorogen-Activating Protein. Nature Methods, 2026,23, 960-971.

(3)  Fangting Zuo; Li Jiang (Co-first author); Ni Su; Yaqiang Zhang; Bingkun Bao; Limei Wang; Yajie Shi; Huimin Yang; Xinyi Huang; Ruilong Li; Qingmei Zeng; Zhengda Chen; Qiuning Lin; Yingping Zhuang; Yuzheng Zhao; Xianjun Chen*; Linyong Zhu*; Yi Yang*; Imaging the Dynamics of Messenger RNA in Live Cells with Highly Bright and Stable Green Fluorescent RNA, Nature Chemcial Biology, 2024, 20: 1272-1281.

(4) Zhengda Chen†, Yajie Shi†, Li Jiang*, Yuxin Yin, Lipeng Yang, Xinyi Huang, Ling Jiang, Wenjie Guo, Xiaoyu Liu, Rong Fu, Huining Liu, Bingkun Bao, Qiuning Lin, Yuzheng Zhao, Xianjun Chen*, Yi Yang*, and Linyong Zhu*, A general strategy for developing Si-rhodamine-based fluorogenic dyes for advanced bioimaging and biosensing, Journal of the American Chemical Society, 2026, DOI: 10.1021/jacs.6c06089.

(5)  Li Jiang; Fangting Zuo; Yuanyuan Pan; Ruilong Li; Yajie Shi; Xinyi Huang; Dasheng Zhang; Yingping Zhuang; Yuzheng Zhao; Qiuning Lin; Yi Yang; Linyong Zhu*; Xianjun Chen*; Bright and Stable Cyan Fluorescent RNA Enables Multicolor RNA Imaging in Live Escherichia coli, Small, 2024, 2405165.

(6)  Xinyi Huang; Yajie Shi; Li Jiang*(Corresponding author); Wanqi Chen; Bingkun Bao; Tuan Liu; Qinghai Zhou; Jiaxin Li; Qiuning Lin*; Linyong Zhu; Precise photorelease in living cells by high-viscosity activatable coumarin-based photocages, Chemical Science, 2025, 16: 3611-3619.

科研项目

（1）国家自然科学基金青年基金，主持

（2）上海市自然科学基金面上项目，主持；

（3）中国博士后科学基金第18批特别资助，主持；

（4）国家自然科学基金重点项目，在研，骨干

（5）国家重点研发计划重点专项，在研，骨干

获奖情况

1．2023年，第二届全国博士后创新创业大赛 银奖

2．2022年，上海市“超级博士后”

3．2022年，上海市博士后创新创业大赛优胜奖